As a continent, Africa is affected by AIDS more than any other region in the world.
In South Africa, more than six million people - or 10% of the entire population - are infected with HIV. The United States is a big financial backer of AIDS-treatment programs there, and South Africa has the largest anti-retroviral program in the world.
Nonetheless, more people are now living with HIV in South Africa than 10 years ago.
CNN's Christiane Amanpour spoke on Monday with U.S. Ambassador to South Africa Patrick Gaspard about HIV/AIDS and the future of the Rainbow Nation; click above to watch their interview.